SCHEMBL147608

SCHEMBL147608

Nc1cccc(C(=O)c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 1.00
ATM Q13315 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
NPC1 O15118 1/20 0.65
MITF O75030 1/20 0.65
LMNA P02545 1/20 0.65
POLB P06746 1/20 0.65
ALDH1A1 P00352 1/20 0.61
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
CA9 Q16790 1/20 0.60
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
SRD5A2 P31213 1/20 0.52
STS P08842 1/20 0.51
MAPT P10636 2/20 0.50
NOX1 Q9Y5S8 1/20 0.50
PTGS1 P23219 1/20 0.50
CXCR1 P25024 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9646439 0.98 PBRM1 (0.96) PBRM1ATMTDP1L3MBTL1NPC1
Benzene SCHEMBL8764875 0.93 PBRM1 (0.88) PBRM1ATMTDP1L3MBTL1NPC1
SCHEMBL29492473 0.93 PBRM1 (0.88) PBRM1ATMTDP1L3MBTL1NPC1
SCHEMBL9097509 0.93 PBRM1 (0.88) PBRM1ATMTDP1L3MBTL1NPC1
SCHEMBL203373 0.93 PBRM1 (0.88) PBRM1ATMTDP1L3MBTL1NPC1
SCHEMBL29363032 0.93 PBRM1 (0.87) PBRM1ATMTDP1L3MBTL1NPC1
SCHEMBL9282073 0.93 PBRM1 (0.87) PBRM1ATMTDP1L3MBTL1NPC1
SCHEMBL125621 0.93 PBRM1 (0.87) PBRM1ATMTDP1L3MBTL1NPC1
Hydrochloric Acid SCHEMBL8643223 0.91 PBRM1 (0.83) PBRM1ATMTDP1L3MBTL1NPC1
SCHEMBL29492479 0.91 PBRM1 (0.83) PBRM1ATMTDP1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12440607-B2 Multifunctional crosslinkers: compounds, compositions, and products thereof BIOCOAT, INCORPORATED (US) 2025-10-14 US claimed
CN-119464808-B Soft magnetic composite material and preparation method thereof 杭州新川新材料有限公司 2025-05-06 CN claimed
CN-119570164-A High-weather-resistance spectrum plastic particle and preparation method thereof 广德全诚新材料有限公司 2025-03-07 CN claimed
CN-119464808-A Soft magnetic composite material and preparation method thereof 杭州新川新材料有限公司 2025-02-18 CN claimed
CN-118119593-A Multifunctional crosslinking agent: compounds, compositions and products thereof 生物涂层有限公司 2024-05-31 CN claimed
EP-4370498-A1 MULTIFUNCTIONAL CROSSLINKERS: COMPOUNDS, COMPOSITIONS, AND PRODUCTS THEREOF Biocoat, Incorporated (US) 2024-05-22 EP claimed
CN-116855225-B UV-thermal dual-curing organic silica gel adhesive and preparation method thereof 韦尔通科技股份有限公司 2024-04-16 CN claimed
CN-116855225-A UV-thermal dual-curing organic silica gel adhesive and preparation method thereof 韦尔通科技股份有限公司 2023-10-10 CN claimed
CN-116731375-A Polymer surface modification method, obtained surface modified polymer and application thereof 中国科学院赣江创新研究院 2023-09-12 CN claimed
US-20230027324-A1 Multifunctional Crosslinkers: Compounds, Compositions, And Products Thereof WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2023-01-26 US claimed
EP-1819341-A2 IL-12 MODULATORY COMPOUNDS Synta Pharmaceuticals Corporation (US) 2007-08-22 EP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
WO-2007034035-A1 SULPHONAMIDE DERIVATIVES BIOTIE THERAPIES CORPORATION (FI) 2007-03-29 WO claimed
WO-2007031608-A1 COLLAGEN RECEPTOR I-DOMAIN BINDING MODULATORS BIOTIE THERAPIES CORPORATION (FI) 2007-03-22 WO claimed
US-20060223996-A1 IL-12 modulatory compounds SYNTA PHARMACEUTICALS CORP. (US) 2006-10-05 US claimed
WO-2006053227-A2 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORP. (US) 2006-05-18 WO claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
US-6890626-B1 Imide-benzoxazole polycondensate and process for producing the same PI R&D CO., LTD. (JP) 2005-05-10 US claimed
WO-2002028353-A2 PHOSPHATE TRANSPORT INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2002-04-11 WO claimed
US-5260388-A Reacting aromatic diamine with tetracarboxylic anhydride in presence of aromatic dicarboxylic anhydride or monoamine, imidizing; low dielectric characteristics; electronics MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223996-A1 IL-12 modulatory compounds IL2, IL4, IFNG PBRM1 3010/4885ATM 4046/4885TDP1 4729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.