SCHEMBL5311622

SCHEMBL5311622

CC(C)NS(=O)(=O)c1cc(C(=O)CCC[CH]C(C)(C)C)cc2c1OCC2

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.45
PTGS2 P35354 4/20 0.45
NPSR1 Q6W5P4 1/20 0.33
ALOX5 P09917 2/20 0.32
PKLR P30613 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5313768 0.89 PTGS2 (0.47) PTGS1PTGS2ALOX5
SCHEMBL4856564 0.85 PTGS2 (0.45) PTGS1PTGS2NPSR1ALOX5PKLR
SCHEMBL5982205 0.75 PTGS1 (0.37) PTGS1PTGS2PKLR
SCHEMBL5981934 0.75 PTGS1 (0.37) PTGS1PTGS2PKLR
Hydrochloric Acid SCHEMBL4858674 0.74 PTGS1 (0.36) PTGS1PTGS2PKLR
Hydrochloric Acid SCHEMBL4855292 0.74 PTGS1 (0.36) PTGS1PTGS2PKLR
SCHEMBL5982195 0.73 SLC2A1 (0.40) PTGS1PTGS2NPSR1
SCHEMBL5982162 0.73 NPSR1 (0.38) PTGS1PTGS2NPSR1
SCHEMBL4857154 0.73 PTGS2 (0.47) PTGS1PTGS2ALOX5PKLR
SCHEMBL5308099 0.73 PTGS1 (0.36) PTGS1PTGS2NPSR1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007052831-A1 PREVENTIVES/REMEDIES FOR URINARY DISTURBANCE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-05-10 WO disclosed