Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 17/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316132 | 0.95 | OPRD1 (0.62) | OPRD1KCNH2 | |
| SCHEMBL5316129 | 0.95 | OPRD1 (0.62) | OPRD1KCNH2 | |
| SCHEMBL5315115 | 0.86 | OPRD1 (0.67) | OPRD1KCNH2 | |
| SCHEMBL5315511 | 0.85 | OPRD1 (0.61) | OPRD1KCNH2KDM4E | |
| SCHEMBL5314016 | 0.85 | OPRD1 (0.61) | OPRD1KCNH2KDM4E | |
| SCHEMBL5314013 | 0.85 | OPRD1 (0.61) | OPRD1KCNH2KDM4E | |
| SCHEMBL5311512 | 0.84 | OPRD1 (0.62) | OPRD1KCNH2 | |
| SCHEMBL5314492 | 0.84 | OPRD1 (0.62) | OPRD1KCNH2 | |
| SCHEMBL14530635 | 0.84 | OPRD1 (0.61) | OPRD1KCNH2 | |
| SCHEMBL14529824 | 0.84 | OPRD1 (0.64) | OPRD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |