Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.41 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 4/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 8/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.35 |
| ▸ | RPS6KA6 | Q9UK32 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312193 | 0.99 | ECE2 (0.42) | ECE2MAP3K12POLBKDRLCK | |
| SCHEMBL5309897 | 0.93 | KDR (0.41) | ECE2KDRLCKTBK1CCNT1 | |
| SCHEMBL5313527 | 0.93 | KDR (0.37) | ECE2KDRLCKTBK1CCNT1 | |
| SCHEMBL5309726 | 0.93 | KDR (0.36) | ECE2KDRLCKTBK1CCNT1 | |
| SCHEMBL5309998 | 0.92 | LCK (0.41) | ECE2KDRLCKTBK1 | |
| SCHEMBL5329362 | 0.92 | KDR (0.40) | KDRLCKTBK1CCNT1FLT3 | |
| SCHEMBL5314105 | 0.91 | KDR (0.38) | ECE2KDRLCKTBK1CCNT1 | |
| SCHEMBL5329616 | 0.90 | KDR (0.35) | ECE2MAP3K12KDRLCKTBK1 | |
| SCHEMBL5328587 | 0.88 | MAP3K12 (0.37) | MAP3K12KDRLCKTBK1 | |
| SCHEMBL5328608 | 0.88 | MAP3K12 (0.37) | MAP3K12KDRLCKTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |