Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 7/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333672 | 1.00 | MAP3K12 (0.37) | MAP3K12LCKITKKDM1AHCK | |
| SCHEMBL5328608 | 1.00 | MAP3K12 (0.37) | MAP3K12LCKITKKDM1AHCK | |
| SCHEMBL5311494 | 0.89 | ITK (0.38) | MAP3K12LCKITKHCKBTK | |
| SCHEMBL5311490 | 0.89 | ITK (0.38) | MAP3K12LCKITKHCKBTK | |
| SCHEMBL5312193 | 0.89 | ECE2 (0.42) | MAP3K12LCKKDRTBK1 | |
| SCHEMBL5314910 | 0.88 | PROKR1 (0.39) | MAP3K12KDM1AHCKBTKSYK | |
| SCHEMBL5312309 | 0.88 | PROKR1 (0.39) | MAP3K12KDM1AHCKBTKSYK | |
| SCHEMBL5312031 | 0.88 | ECE2 (0.41) | MAP3K12LCKKDRTBK1 | |
| SCHEMBL5313527 | 0.87 | KDR (0.37) | LCKKDRSYKTBK1 | |
| SCHEMBL5309897 | 0.87 | KDR (0.41) | LCKKDRSYKTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |