Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 15/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313807 | 0.77 | LTA4H (0.69) | LTA4H | |
| SCHEMBL5662457 | 0.72 | LTA4H (0.68) | LTA4HNPY5R | |
| SCHEMBL5661889 | 0.69 | LTA4H (0.85) | LTA4HNPY5R | |
| SCHEMBL5659966 | 0.67 | LTA4H (1.00) | LTA4H | |
| SCHEMBL5661307 | 0.67 | LTA4H (0.65) | LTA4HNPY5R | |
| SCHEMBL5658771 | 0.67 | LTA4H (0.56) | LTA4HNPY5RUTS2R | |
| SCHEMBL5660215 | 0.65 | LTA4H (0.82) | LTA4HNPY5R | |
| SCHEMBL5312495 | 0.65 | LTA4H (0.74) | LTA4H | |
| SCHEMBL5313799 | 0.65 | MAPT (0.62) | LTA4H | |
| SCHEMBL5656997 | 0.65 | LTA4H (0.62) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | claimed |