Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334985 | 1.00 | GSK3B (0.50) | GSK3BAKR1C3ERCC5FEN1HDAC8 | |
| SCHEMBL5310279 | 0.86 | AKR1C3 (0.46) | AKR1C3ERCC5FEN1HDAC8TLR4 | |
| SCHEMBL434112 | 0.82 | GSK3B (0.70) | GSK3BALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL28778258 | 0.82 | GSK3B (0.70) | GSK3BALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL437419 | 0.82 | GSK3B (0.70) | GSK3BALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL5334684 | 0.77 | KMT2A (0.39) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL5315685 | 0.74 | FFAR1 (0.49) | AKR1C3ALDH1A1LMNAKMT2AMAOB | |
| SCHEMBL5315690 | 0.74 | FFAR1 (0.49) | AKR1C3ALDH1A1LMNAKMT2AMAOB | |
| SCHEMBL5312318 | 0.73 | ERCC5 (0.67) | GSK3BAKR1C3ERCC5FEN1HDAC8 | |
| SCHEMBL23292494 | 0.72 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |