Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310279 | 0.82 | AKR1C3 (0.46) | KMT2AMAPTALDH1A1NPC1POLB | |
| SCHEMBL5342195 | 0.80 | GSK3B (0.50) | KMT2AMAPTALDH1A1NPC1CYP2C9 | |
| SCHEMBL14530949 | 0.78 | PLA2G4B (0.48) | KMT2AP2RX3PPARGMAOAMAOB | |
| SCHEMBL5334985 | 0.77 | GSK3B (0.50) | KMT2AALDH1A1NPC1POLBCYP2C9 | |
| SCHEMBL5312481 | 0.77 | GSK3B (0.50) | KMT2AALDH1A1NPC1POLBCYP2C9 | |
| SCHEMBL5332467 | 0.75 | KMT2A (0.42) | KMT2AMAPTP2RX3NPC1POLB | |
| SCHEMBL5332472 | 0.75 | KMT2A (0.42) | KMT2AMAPTP2RX3NPC1POLB | |
| SCHEMBL5798676 | 0.72 | LTA4H (0.46) | NPC1RAB9ASMN1; SMN2PARP10 | |
| SCHEMBL5823156 | 0.72 | LTA4H (0.46) | NPC1RAB9ASMN1; SMN2PARP10 | |
| SCHEMBL5312903 | 0.72 | KMT2A (0.59) | KMT2AALDH1A1NPC1POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |