Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 4/20 | 0.38 |
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 6/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334096 | 1.00 | HCK (0.38) | HCKBTKPROKR1IRAK4SCN9A | |
| SCHEMBL5312665 | 1.00 | HCK (0.38) | HCKBTKPROKR1IRAK4SCN9A | |
| SCHEMBL14530643 | 0.91 | HCK (0.39) | HCKBTKPROKR1SYKITK | |
| SCHEMBL14531392 | 0.89 | PROKR1 (0.40) | HCKBTKPROKR1IRAK4SYK | |
| SCHEMBL5310631 | 0.89 | PROKR1 (0.40) | HCKBTKPROKR1SYK | |
| SCHEMBL5312309 | 0.89 | PROKR1 (0.39) | HCKBTKPROKR1SYK | |
| SCHEMBL5314910 | 0.89 | PROKR1 (0.39) | HCKBTKPROKR1SYK | |
| SCHEMBL5311490 | 0.89 | ITK (0.38) | HCKBTKSYKITK | |
| SCHEMBL5311494 | 0.89 | ITK (0.38) | HCKBTKSYKITK | |
| SCHEMBL5312760 | 0.87 | PROKR1 (0.37) | HCKBTKPROKR1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |