Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 5/20 | 0.39 |
| ▸ | BTK | Q06187 | 5/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 6/20 | 0.36 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | CCNH | P51946 | 2/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312665 | 0.91 | HCK (0.38) | HCKBTKPROKR1ITKSYK | |
| SCHEMBL5334096 | 0.91 | HCK (0.38) | HCKBTKPROKR1ITKSYK | |
| SCHEMBL5312669 | 0.91 | HCK (0.38) | HCKBTKPROKR1ITKSYK | |
| SCHEMBL14531392 | 0.89 | PROKR1 (0.40) | HCKBTKPROKR1SYK | |
| SCHEMBL5312309 | 0.88 | PROKR1 (0.39) | HCKBTKPROKR1SYK | |
| SCHEMBL5314910 | 0.88 | PROKR1 (0.39) | HCKBTKPROKR1SYK | |
| SCHEMBL5310631 | 0.88 | PROKR1 (0.40) | HCKBTKPROKR1SYK | |
| SCHEMBL5312760 | 0.86 | PROKR1 (0.37) | HCKBTKPROKR1SYK | |
| SCHEMBL5310717 | 0.86 | IKBKB (0.40) | PROKR1SYKCCNA2CDK2 | |
| SCHEMBL5417532 | 0.84 | CCNT1 (0.43) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |