Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241921 | 1.00 | DPP4 (0.69) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL1241918 | 1.00 | DPP4 (0.69) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL1242707 | 1.00 | DPP4 (0.69) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL1241920 | 1.00 | DPP4 (0.69) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1241932 | 0.99 | DPP4 (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1241930 | 0.99 | DPP4 (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1242733 | 0.99 | DPP4 (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1241935 | 0.99 | DPP4 (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL5263702 | 0.99 | DPP4 (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL1243122 | 0.97 | LMNA (0.72) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187835-B1 | OPTICALLY ACTIVE QUINOLINE CARBOXYLIC ACID DERIVATIVES HAVING 7-PYRROLIDINE SUBSTITUTES CAUSING OPTICAL ACTIVITY AND A PROCESS FOR PREPARING THEREOF | DONG WHA PHARM IND CO LTD (KR) | 2007-12-26 | — | — | EP | claimed |