Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 1.00 |
| ▸ | NR2F2 | P24468 | 1/20 | 1.00 |
| ▸ | EGFR | P00533 | 8/20 | 0.64 |
| ▸ | KRAS | P01116 | 1/20 | 0.64 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.57 |
| ▸ | CDK2 | P24941 | 3/20 | 0.57 |
| ▸ | CDK4 | P11802 | 2/20 | 0.57 |
| ▸ | CCND1 | P24385 | 2/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17181108 | 1.00 | GALR3 (1.00) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL29490300 | 0.88 | GALR3 (0.78) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL28502349 | 0.88 | GALR3 (0.78) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL22862564 | 0.88 | GALR3 (0.78) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL31505701 | 0.84 | GALR3 (0.72) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL13283262 | 0.84 | GALR3 (0.72) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL6837669 | 0.84 | GALR3 (0.72) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL6837666 | 0.84 | GALR3 (0.72) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL31505705 | 0.84 | GALR3 (0.72) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL15889088 | 0.83 | GALR3 (0.71) | GALR3NR2F2EGFRRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |