Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALPL | P05186 | 1/20 | 0.67 |
| ▸ | ALPI | P09923 | 1/20 | 0.67 |
| ▸ | ALPG | P10696 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.57 |
| ▸ | EP300 | Q09472 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | STK17B | O94768 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312808 | 1.00 | KMT2A (0.67) | KMT2AMEN1MAPTALDH1A1ALPL | |
| SCHEMBL30019926 | 0.82 | EP300 (0.65) | KMT2AMEN1MAPTALDH1A1ALPL | |
| SCHEMBL22624945 | 0.80 | KMT2A (1.00) | KMT2AMEN1MAPTALDH1A1ALPL | |
| SCHEMBL29767641 | 0.79 | KMT2A (1.00) | KMT2AMEN1MAPTALDH1A1ALPL | |
| SCHEMBL5673913 | 0.79 | KMT2A (1.00) | KMT2AMEN1MAPTALDH1A1ALPL | |
| SCHEMBL17471561 | 0.76 | MAPT (0.56) | KMT2AMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL12866255 | 0.74 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1ALPL | |
| SCHEMBL7851425 | 0.74 | PDE4B (0.79) | MAPTERBB2APPSNCA | |
| SCHEMBL7843451 | 0.74 | PDE4B (0.79) | MAPTERBB2APPSNCA | |
| SCHEMBL5476200 | 0.74 | DHFR (0.73) | KMT2AMEN1MAPTALDH1A1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |