Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA6 | P23280 | 2/20 | 0.61 |
| ▸ | CA5A | P35218 | 2/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312885 | 1.00 | LMNA (0.67) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL78103 | 0.87 | HCAR2 (0.53) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL2340792 | 0.87 | HCAR2 (0.53) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL21678780 | 0.84 | HCAR2 (0.65) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL78104 | 0.84 | HCAR2 (0.65) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL17800130 | 0.83 | LMNA (0.65) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL5176891 | 0.81 | IDO1 (0.46) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL11716927 | 0.81 | LMNA (0.61) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL11716934 | 0.81 | LMNA (0.61) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL13833759 | 0.80 | LMNA (0.93) | LMNAAKR1B10AKR1B1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803809-A2 | Modulation of peroxisome proliferator-activated receptors | Abgenomics Corporation (TW) | 2007-07-04 | — | — | EP | claimed |
| US-20070037193-A1 | Modulation of peroxisome proliferator-activated receptors | ABGENOMICS CORPORATION (TW) | 2007-02-15 | — | — | US | claimed |
| EP-1803809-A2 | Modulation of peroxisome proliferator-activated receptors | Abgenomics Corporation (TW) | 2007-07-04 | — | — | EP | disclosed |
| US-20070037193-A1 | Modulation of peroxisome proliferator-activated receptors | ABGENOMICS CORPORATION (TW) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037193-A1 | Modulation of peroxisome proliferator-activated receptors | PPARG, PPARA, PPARD | LMNA 2640/4885AKR1B10 75/4885AKR1B1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.