Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | TSHR | P16473 | 2/20 | 0.84 |
| ▸ | BLM | P54132 | 2/20 | 0.84 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.84 |
| ▸ | MPO | P05164 | 1/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL9407071 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL3443032 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL9488111 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL5016074 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4296800 | 0.96 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28697957 | 0.95 | KDM4E (0.76) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL1640623 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL1640625 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL8020249 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL7645018 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642910-B1 | Rationally designed antibodies | ALEXION PHARMA INC (US) | 2012-02-08 | — | — | EP | claimed |
| EP-1589034-B1 | Rationally designed antibodies | ALEXION PHARMA INC (US) | 2008-11-19 | — | — | EP | claimed |
| EP-1642910-A1 | Rationally designed antibodies | ALEXION PHARMACEUTICALS, INC. (US) | 2006-04-05 | — | — | EP | claimed |
| EP-1370589-B1 | RATIONALLY DESIGNED ANTIBODIES | ALEXION PHARMA INC (US) | 2006-03-15 | — | — | EP | claimed |
| EP-1589034-A2 | Rationally designed antibodies | ALEXION PHARMACEUTICALS, INC. (US) | 2005-10-26 | — | — | EP | claimed |
| US-20030049683-A1 | Immunoglobulin for use in human therapeutics and diagnostics | ALEXION PHARMACEUTICAL, INC. | 2003-03-13 | — | — | US | claimed |
| WO-2014002571-A1 | ANGIOTENSIN-CONVERTING-ENZYME INHIBITING DIPEPTIDE | ヤマキ株式会社 (JP) | 2014-01-03 | — | — | WO | disclosed |
| US-5312901-A | Genetic engineering with immunoglobulins and proteins | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1994-05-17 | — | — | US | disclosed |
| US-5141870-A | Transforming plants with mutant fragment confers herbicide resistance | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| US-5082773-A | Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1992-01-21 | — | — | US | disclosed |
| US-4956296-A | GENETIC ENGINEERING | GENEX CORPORATION (US) | 1990-09-11 | — | — | US | disclosed |
| US-4954618-A | IMMUNOGLOBULIN BINDER | GENEX CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |