Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | TSHR | P16473 | 2/20 | 0.84 |
| ▸ | BLM | P54132 | 2/20 | 0.84 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.84 |
| ▸ | MPO | P05164 | 1/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL9407071 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL531307 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL3443032 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL5016074 | 1.00 | KMT2A (0.84) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4296800 | 0.96 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28697957 | 0.95 | KDM4E (0.76) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL1640623 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL1640625 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL8020249 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL7645018 | 0.92 | KMT2A (0.94) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229492-A | Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1993-07-20 | — | — | US | disclosed |
| EP-0363436-A4 | CLONED PROTEIN G VARIANT GENES AND THE PROTEIN G VARIANTS EXPRESSED THEREFROM. | GENEX CORP (US) | 1990-06-26 | — | — | EP | disclosed |
| EP-0363436-A1 | CLONED PROTEIN G VARIANT GENES AND THE PROTEIN G VARIANTS EXPRESSED THEREFROM | Pharmacia LKB Biotechnology AB (SE) | 1990-04-18 | — | — | EP | disclosed |
| EP-0293391-A4 | CLONED STREPTOCOCCAL GENES ENCODING PROTEIN G AND THEIR USE TO CONSTRUCT RECOMBINANT MICROORGANISMS TO PRODUCE PROTEIN G. | GENEX CORP (US) | 1989-06-21 | — | — | EP | disclosed |
| WO-1988010306-A1 | CLONED PROTEIN G VARIANT GENES AND THE PROTEIN G VARIANTS EXPRESSED THEREFROM | GENEX CORPORATION (US) | 1988-12-29 | — | — | WO | disclosed |
| EP-0293391-A1 | CLONED STREPTOCOCCAL GENES ENCODING PROTEIN G AND THEIR USE TO CONSTRUCT RECOMBINANT MICROORGANISMS TO PRODUCE PROTEIN G | Pharmacia LKB Biotechnology AB (SE) | 1988-12-07 | — | — | EP | disclosed |
| WO-1987005025-A1 | CLONED STREPTOCOCCAL GENES ENCODING PROTEIN G AND THEIR USE TO CONSTRUCT RECOMBINANT MICROORGANISMS TO PRODUCE PROTEIN G | GENEX CORPORATION (US) | 1987-08-27 | — | — | WO | disclosed |