Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 3/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | CRACR2A | Q9BSW2 | 3/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311743 | 0.90 | TYK2 (0.47) | LMNAHSD17B10SCDTYK2FLT3 | |
| SCHEMBL5311966 | 0.84 | SCD (0.45) | LMNAHSD17B10SCDFLT3CRACR2A | |
| SCHEMBL5313775 | 0.84 | MEN1 (0.39) | LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL5314287 | 0.79 | SCD (0.44) | SCDKDM4EALDH1A1 | |
| SCHEMBL5334708 | 0.78 | RBP4 (0.42) | LMNAHSD17B10SCDMAPTALDH1A1 | |
| SCHEMBL5308717 | 0.78 | SCD (0.46) | SCDALDH1A1HPGDRBP4 | |
| SCHEMBL5313105 | 0.77 | SCD (0.44) | LMNASCDALDH1A1GAAHPGD | |
| SCHEMBL5314274 | 0.76 | MEN1 (0.39) | LMNASCDMAPTKDM4EALDH1A1 | |
| SCHEMBL5311238 | 0.75 | SCD (0.56) | LMNAHSD17B10SCDKDM4EALDH1A1 | |
| SCHEMBL14542704 | 0.74 | SCD (0.58) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |