Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 4/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314821 | 0.93 | CACNA1F (0.51) | CACNA1FCACNA1DCACNA1SCACNA1CKDM4E | |
| SCHEMBL5311848 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1POLBLMNAAGTR1 | |
| SCHEMBL3324462 | 0.90 | CACNA1F (0.50) | CACNA1FCACNA1DCACNA1SCACNA1CKDM4E | |
| SCHEMBL5334676 | 0.89 | ALDH1A1 (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CKDM4E | |
| SCHEMBL5311773 | 0.89 | PDE1C (0.52) | KDM4EALDH1A1POLBLMNAAGTR1 | |
| SCHEMBL5332348 | 0.88 | KDM4E (0.51) | KDM4EALDH1A1POLBLMNAAGTR1 | |
| SCHEMBL12932104 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1POLBLMNAAGTR1 | |
| SCHEMBL5312208 | 0.88 | KDM4E (0.66) | CACNA1FCACNA1DCACNA1SCACNA1CKDM4E | |
| SCHEMBL5309384 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1POLBLMNAAGTR1 | |
| SCHEMBL31634797 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1POLBLMNAAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051062-A2 | SUBSTITUTED DIHYDROPYRIDINES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-05-03 | — | — | WO | disclosed |