Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | CCR3 | P51677 | 4/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310518 | 0.86 | POLB (0.44) | SIGMAR1MCHR1ALDH1A1 | |
| SCHEMBL5657208 | 0.84 | LTA4H (0.61) | CHRM4LTA4HSIGMAR1SLC6A12TMEM97 | |
| SCHEMBL5313297 | 0.81 | LTA4H (0.67) | LTA4HCCR3 | |
| SCHEMBL5333591 | 0.80 | LTA4H (0.71) | CHRM4LTA4H | |
| SCHEMBL5310237 | 0.75 | LTA4H (0.62) | CHRM4LTA4H | |
| SCHEMBL5313759 | 0.75 | LTA4H (0.61) | CHRM4LTA4HSIGMAR1 | |
| SCHEMBL5309936 | 0.73 | LTA4H (0.58) | CHRM4LTA4HPRKAA2 | |
| SCHEMBL5312584 | 0.72 | LTA4H (0.54) | LTA4HSIGMAR1SLC6A12MCHR1 | |
| SCHEMBL5310158 | 0.71 | LTA4H (0.56) | CHRM4LTA4H | |
| SCHEMBL5661120 | 0.71 | LTA4H (0.55) | LTA4HMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | claimed |