Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL144254 | 0.88 | PPARA (0.51) | ACHEPPARGPPARA | |
| SCHEMBL15823267 | 0.86 | CYP4F2 (0.51) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| Hydrochloric Acid SCHEMBL15823735 | 0.85 | CYP4F2 (0.50) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL7053659 | 0.84 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL14528299 | 0.80 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL7051306 | 0.80 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL1045800 | 0.79 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL14415671 | 0.77 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL5161046 | 0.77 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL7050753 | 0.77 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831799-B1 | COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS | NPS PHARMA INC (US) | 2003-05-02 | — | — | EP | claimed |
| US-7217696-B2 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | A & D BIOSCIENCE, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| WO-2007041463-A2 | ELECTRICAL DEVICES AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20050130908-A1 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | HOLICK MICHAEL F (US) | 2005-06-16 | — | — | US | disclosed |
| EP-1487460-A2 | GLYCURONAMIDES, GLYCOSIDES AND ORTHOESTER GLYCOSIDES OF FLUOXETINE, ANALOGS AND USES THEREOF | A & D Bioscience, Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003073988-A2 | GLYCURONAMIDES, GLYCOSIDES AND ORTHOESTER GLYCOSIDES OF FLUOXETINE, ANALOGS AND USES THEREOF | A & D BIOSCIENCE, INC. (US) | 2003-09-12 | — | — | WO | disclosed |
| EP-0831799-B1 | COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS | NPS PHARMA INC (US) | 2003-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130908-A1 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | PYGB, GBA3, GAA | SLC6A4 121/4885SLC6A2 130/4885SLC6A3 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.