Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313664 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5313697 | 0.92 | MAPT (0.45) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5313691 | 0.92 | MAPT (0.45) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5314639 | 0.91 | RAB9A (0.49) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5314642 | 0.91 | RAB9A (0.49) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5316156 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5316159 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5311834 | 0.83 | MAPT (0.47) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5311831 | 0.83 | MAPT (0.47) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL5310815 | 0.81 | PTPN1 (0.40) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |