Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 19/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311807 | 0.92 | CCR2 (0.50) | CCR2KCNH2 | |
| SCHEMBL5311389 | 0.90 | CCR2 (0.48) | CCR2KCNH2 | |
| SCHEMBL5309114 | 0.89 | CCR2 (0.45) | CCR2KCNH2 | |
| SCHEMBL5309500 | 0.89 | CCR2 (0.52) | CCR2KCNH2 | |
| SCHEMBL5311870 | 0.87 | CCR2 (0.48) | CCR2KCNH2 | |
| SCHEMBL5312327 | 0.87 | CCR2 (0.52) | CCR2KCNH2GPR139 | |
| SCHEMBL5312494 | 0.86 | CCR2 (0.49) | CCR2KCNH2GPR139 | |
| SCHEMBL5311594 | 0.86 | CCR2 (0.46) | CCR2KCNH2 | |
| SCHEMBL5313062 | 0.86 | CCR2 (0.45) | CCR2KCNH2 | |
| SCHEMBL5312516 | 0.86 | KCNH2 (0.45) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053495-A2 | COMPOUNDS USEFUL AS ANTAGONISTS OF CCR2 | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-05-10 | — | — | WO | disclosed |