SCHEMBL5313857

SCHEMBL5313857

COC(=O)C(O)CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7610432 1.00
SCHEMBL29253175 0.86 CA1 (0.41)
SCHEMBL29062658 0.84 ZDHHC7 (0.41)
SCHEMBL9532724 0.82 ZDHHC7 (0.44)
SCHEMBL21552785 0.82 ZDHHC7 (0.44)
SCHEMBL14057228 0.82 ZDHHC7 (0.44)
SCHEMBL21551862 0.82 ZDHHC7 (0.44)
SCHEMBL20816344 0.82 ZDHHC7 (0.44)
SCHEMBL3792348 0.82 ZDHHC7 (0.44)
SCHEMBL2229956 0.82 ZDHHC7 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145034-A1 ALKYNYL ALCOHOLS AND METHODS OF USE GENENTECH, INC. (US) 2017-05-25 US disclosed
US-20170145034-A1 ALKYNYL ALCOHOLS AND METHODS OF USE GENENTECH, INC. (US) 2017-05-25 US disclosed
US-20170145034-A1 ALKYNYL ALCOHOLS AND METHODS OF USE GENENTECH, INC. (US) 2017-05-25 US disclosed
US-9605005-B2 Alkynyl alcohols and methods of use GENENTECH, INC. (US) 2017-03-28 US disclosed
US-9605005-B2 Alkynyl alcohols and methods of use GENENTECH, INC. (US) 2017-03-28 US disclosed
US-9605005-B2 Alkynyl alcohols and methods of use GENENTECH, INC. (US) 2017-03-28 US disclosed
US-20160200739-A1 ALKYNYL ALCOHOLS AND METHODS OF USE GENENTECH, INC. (CA) 2016-07-14 US disclosed
US-20160200739-A1 ALKYNYL ALCOHOLS AND METHODS OF USE GENENTECH, INC. (CA) 2016-07-14 US disclosed
US-20160200739-A1 ALKYNYL ALCOHOLS AND METHODS OF USE GENENTECH, INC. (CA) 2016-07-14 US disclosed
EP-3036230-A1 ALKYNYL ALCOHOLS AND METHODS OF USE F. Hoffmann-La Roche AG (CH) 2016-06-29 EP disclosed
WO-2004048360-A1 METHOD OF SYNTHESIZING MACROSPHELIDES LEAD CHEMICAL CO., LTD. (JP) 2004-06-10 WO disclosed
EP-0863872-B1 PREPARATION OF CHIRAL 3-HYDROXY-2-PYRROLIDINONE DERIVATIVES SYNGENTA LTD (GB) 2002-05-29 EP disclosed
EP-1027343-A4 PROCESS FOR THE PREPARATION OF HYDROXY SUBSTITUTED GAMMA BUTYROLACTONES UNIV MICHIGAN STATE (US) 2001-08-22 EP disclosed
EP-1027343-A1 PROCESS FOR THE PREPARATION OF HYDROXY SUBSTITUTED GAMMA BUTYROLACTONES MICHIGAN STATE UNIVERSITY (US) 2000-08-16 EP disclosed
CN-1262317-A Ether ester type dry cleaning solvent composition LI JINYAN (CN) 2000-08-09 CN disclosed
WO-1999023086-A1 PROCESS FOR THE PREPARATION OF HYDROXY SUBSTITUTED GAMMA BUTYROLACTONES MICHIGAN STATE UNIVERSITY (US) 1999-05-14 WO disclosed
EP-0863872-A1 PREPARATION OF CHIRAL 3-HYDROXY-2-PYRROLIDINONE DERIVATIVES ZENECA LIMITED (GB) 1998-09-16 EP disclosed
US-5710283-A Preparation of chiral pyrrolidinone derivatives ZENECA LIMITED (GB) 1998-01-20 US disclosed
WO-1997019920-A1 PREPARATION OF CHIRAL 3-HYDROXY-2-PYRROLIDINONE DERIVATIVES ZENECA LIMITED (GB) 1997-06-05 WO disclosed
EP-0339618-A2 Method for preparing optically active 3,4-dihydroxy butyric acid derivatives KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-11-02 EP disclosed