Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552785 | 1.00 | ZDHHC7 (0.44) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL20816344 | 1.00 | ZDHHC7 (0.44) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL14057228 | 1.00 | ZDHHC7 (0.44) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL3792348 | 1.00 | ZDHHC7 (0.44) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL21551862 | 1.00 | ZDHHC7 (0.44) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL2229956 | 1.00 | ZDHHC7 (0.44) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL28275336 | 1.00 | ZDHHC7 (0.44) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL29062658 | 0.98 | ZDHHC7 (0.41) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL29253175 | 0.91 | CA1 (0.41) | ZDHHC7GPR84FFAR1CA1CA2 | |
| SCHEMBL15953257 | 0.89 | DGKA (0.39) | ZDHHC7FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |