Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540740 | 1.00 | SLC7A5 (0.44) | SLC7A5SOAT1FFAR1PTGS1ALPI | |
| SCHEMBL20943291 | 0.84 | FFAR1 (0.47) | SLC7A5FFAR1PTGS1ALPIPKM | |
| SCHEMBL5306700 | 0.82 | SLC7A5 (0.60) | SLC7A5FFAR1CA2ESR1 | |
| SCHEMBL14540739 | 0.82 | SLC7A5 (0.60) | SLC7A5FFAR1CA2ESR1 | |
| SCHEMBL14541035 | 0.82 | SLC7A5 (0.60) | SLC7A5FFAR1CA2ESR1 | |
| SCHEMBL14269025 | 0.81 | LDHA (0.57) | SLC7A5SOAT1PTGS1ALPIPKM | |
| SCHEMBL246475 | 0.81 | CYP1A2 (0.61) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL25210806 | 0.80 | PPARG (0.54) | — | |
| SCHEMBL7419589 | 0.80 | PPARG (0.47) | FFAR1PTGS1TSHRTDP1PTGS2 | |
| SCHEMBL12266029 | 0.80 | PPARG (0.47) | FFAR1PTGS1TSHRTDP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039125-A2 | AN OPTICALLY ACTIVE THYROID RECEPTOR AGONIST AND OPTICALLY ACTIVE KEY INTERMEDIATES IN ITS PRODUCTION | KARO BIO AB (SE) | 2007-04-12 | — | — | WO | disclosed |