⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408595 | 0.92 | TSHR (0.35) | — | |
| SCHEMBL14673800 | 0.89 | TSHR (0.39) | — | |
| SCHEMBL3056886 | 0.89 | TSHR (0.39) | — | |
| SCHEMBL9126036 | 0.89 | TSHR (0.39) | — | |
| SCHEMBL31756933 | 0.89 | TSHR (0.39) | — | |
| SCHEMBL8438526 | 0.89 | TSHR (0.39) | — | |
| SCHEMBL8741680 | 0.89 | TSHR (0.39) | — | |
| SCHEMBL27854821 | 0.86 | — | — | |
| SCHEMBL1095770 | 0.81 | — | — | |
| SCHEMBL823000 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624210-A | Synthesis method of hydroxypropyl trimethylsilane | 内蒙古三友化学有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-121873113-A | Synthesis method of 3-bromopropoxy trimethylsilane | 内蒙古三友化学有限公司 | 2026-04-17 | — | — | CN | disclosed |
| CN-117624210-A | Synthesis method of hydroxypropyl trimethylsilane | 内蒙古三友化学有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117624210-A | Synthesis method of hydroxypropyl trimethylsilane | 内蒙古三友化学有限公司 | 2024-03-01 | — | — | CN | disclosed |
| EP-2308308-B1 | Stable aqueous solutions of silane quat ammonium compounds | CHURCH & DWIGHT CO INC (US) | 2015-08-05 | — | — | EP | disclosed |
| US-8956665-B2 | Stable aqueous solutions of silane quat ammonium compounds | CHURCH & DWIGHT CO., INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8841283-B2 | Methods for the preparation of drospirenone and intermediates thereof | NEWCHEM S.P.A. (IT) | 2014-09-23 | — | — | US | disclosed |
| US-8841283-B2 | Methods for the preparation of drospirenone and intermediates thereof | NEWCHEM S.P.A. (IT) | 2014-09-23 | — | — | US | disclosed |
| EP-2601206-A1 | METHODS FOR THE PREPARATION OF DROSPIRENONE AND INTERMEDIATES THEREOF | Newchem S.p.A. (IT) | 2013-06-12 | — | — | EP | disclosed |
| US-20130131335-A1 | METHODS FOR THE PREPARATION OF DROSPIRENONE AND INTERMEDIATES THEREOF | NEWCHEM S.P.A. (IT) | 2013-05-23 | — | — | US | disclosed |
| EP-1611121-A1 | PYRIDAZINONE DERIVATIVES AS CDK2-INHIBITORS | Aventis Pharma S.A. (FR) | 2006-01-04 | — | — | EP | disclosed |
| EP-1581505-A1 | PYRIDAZINONE DERIVATIVES AS GSK-3BETA INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2005-10-05 | — | — | EP | disclosed |
| US-20050026918-A1 | Novel pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-02-03 | — | — | US | disclosed |
| US-20040176377-A1 | Novel pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| WO-2004046117-A1 | PYRIDAZINONE DERIVATIVES AS GSK-3BETA INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-03 | — | — | WO | disclosed |
| WO-2004046130-A1 | PYRIDAZINONE DERIVATIVES AS CDK2-INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-06-03 | — | — | WO | disclosed |
| US-20030114611-A1 | Functionalized alkyllithium formulations with improved thermal stability and processes for making the same | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20030114592-A1 | Processes for improving stability of living polymer chain ends | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-5622784-A | WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM | SEIKO EPSON CORPORATION (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5403946-A | Process of preparing trimethylsilyloxy functionalized alkyllithium compounds | FMC CORPORATION (US) | 1995-04-04 | — | — | US | disclosed |