Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741680 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL3056886 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL31756933 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL9126036 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL14673800 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL8408595 | 0.97 | TSHR (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL531396 | 0.89 | — | — | |
| SCHEMBL20483089 | 0.86 | — | — | |
| SCHEMBL16295146 | 0.86 | — | — | |
| SCHEMBL9284273 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675130-B1 | Process for the preparation of phosphonium salts | SHINETSU CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |
| US-5481040-A | REACTING A PHOSPHINE WITH A CHLORIDE IN THE PRESENCE OF AN ALKALI METAL SALT AND A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0675130-A2 | Process for the preparation of phosphonium salts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |