Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079191 | 0.85 | HTT (0.64) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7514786 | 0.85 | HTT (0.73) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6431191 | 0.85 | HTT (0.64) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL127662 | 0.84 | HTT (0.82) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4173649 | 0.84 | HTT (0.62) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6648982 | 0.84 | HTT (0.62) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7511539 | 0.84 | HTT (0.67) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13055383 | 0.84 | LMNA (0.80) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7400993 | 0.83 | HTT (0.79) | HTTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10950730 | 0.82 | HTT (0.61) | HTTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007035964-A2 | VIGABATRIN BIOISOTERES AND RELATED METHODS OF USE | NORTHWESTERN UNIVERSITY (US) | 2007-03-29 | — | — | WO | disclosed |