Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.55 |
| ▸ | POLG | P54098 | 1/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 2/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091449 | 1.00 | POLB (0.59) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL2388172 | 0.92 | POLB (0.59) | POLBP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL9014008 | 0.92 | POLB (0.59) | POLBP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL31128188 | 0.90 | POLB (0.60) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL18392223 | 0.88 | POLB (0.58) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL23389903 | 0.85 | POLB (0.53) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL154964 | 0.85 | POLB (0.55) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL5315097 | 0.85 | TGM2 (0.58) | P2RY2P2RY4P2RY6FUT5TGM2 | |
| SCHEMBL5315091 | 0.85 | TGM2 (0.58) | P2RY2P2RY4P2RY6FUT5TGM2 | |
| Deoxyguanosine Triphosphate SCHEMBL2820367 | 0.84 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153745-A | A TRIPHOSPHATE, DIPHOSPHATE AND THIOTRIPHOSPHATE FOR REPLICATING A TEMPLATE DNA SEQUENC TO FORM NON-IDENTICAL COPIES OF THE TEMPLATE SEQUENCE | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-11-28 | — | — | US | claimed |
| WO-2007061237-A1 | COMPOSITION FOR ANTI-INFLAMMATION | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-05-31 | — | — | WO | disclosed |
| US-20040072168-A1 | Novel deoxynucleoside kinase enzyme variants | KNECHT WOLFGANG (SE) | 2004-04-15 | — | — | US | disclosed |
| EP-1283874-A2 | NOVEL DEOXYNUCLEOSIDE KINASE ENZYME VARIANTS | Knecht, Wolfgang (DK) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001088106-A2 | NOVEL DEOXYRIBONUCLESIDE KINASE ENZYME MULTI-SUBSTRATE VARIANTS | KNECHT WOLFGANG (DK) | 2001-11-22 | — | — | WO | disclosed |
| EP-0866796-B1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2000-11-29 | — | — | EP | disclosed |
| US-6153745-A | A TRIPHOSPHATE, DIPHOSPHATE AND THIOTRIPHOSPHATE FOR REPLICATING A TEMPLATE DNA SEQUENC TO FORM NON-IDENTICAL COPIES OF THE TEMPLATE SEQUENCE | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-11-28 | — | — | US | disclosed |
| EP-0866796-A1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | MEDICAL RESEARCH COUNCIL (GB) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997011083-A1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | MEDICAL RESEARCH COUNCIL (GB) | 1997-03-27 | — | — | WO | disclosed |