Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.76 |
| ▸ | GAA | P10253 | 6/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30731679 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL30731742 | 0.80 | ALDH1A1 (0.85) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL30731691 | 0.80 | ALDH1A1 (0.85) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL28304642 | 0.80 | ALDH1A1 (0.88) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL28304646 | 0.80 | ALDH1A1 (1.00) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL5311525 | 0.78 | ALDH1A1 (0.76) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL5314276 | 0.78 | ALDH1A1 (0.76) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL5313341 | 0.78 | ALDH1A1 (0.80) | ALDH1A1GAASMN1; SMN2LMNASGMS2 | |
| SCHEMBL5311098 | 0.77 | ALDH1A1 (0.74) | ALDH1A1GAASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL5314490 | 0.77 | ALDH1A1 (0.74) | ALDH1A1GAASMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |