Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3289212 | 0.90 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL5315786 | 0.89 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL3288575 | 0.89 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL3291182 | 0.85 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL3293700 | 0.81 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL3288241 | 0.81 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL3292495 | 0.81 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL3288785 | 0.81 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL3288268 | 0.79 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL3290164 | 0.79 | P2RX7 (0.61) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747206-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111003-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |