Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde SCHEMBL872657 | 0.92 | ALDH1A1 (0.42) | ALDH1A1CYP2A6KMT2AMEN1LMNA | |
| Benzaldehyde SCHEMBL4954589 | 0.90 | ALDH1A1 (0.47) | ALDH1A1CYP2A6KMT2AMEN1LMNA | |
| Benzaldehyde SCHEMBL367504 | 0.90 | ALDH1A1 (0.54) | ALDH1A1CYP2A6KMT2AMEN1LMNA | |
| Sorbitol SCHEMBL1276725 | 0.90 | ALDH1A1 (0.40) | ALDH1A1CYP2A6KMT2AMEN1LMNA | |
| Benzaldehyde SCHEMBL17698491 | 0.87 | ALDH1A1 (0.38) | ALDH1A1CYP2A6KMT2AMEN1LMNA | |
| Benzaldehyde SCHEMBL11346796 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CYP2A6KMT2AMEN1LMNA | |
| Benzaldehyde SCHEMBL2536104 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CYP2A6KMT2ALMNAL3MBTL1 | |
| Benzaldehyde SCHEMBL10821733 | 0.86 | ALDH1A1 (0.42) | ALDH1A1CYP2A6KMT2AMEN1LMNA | |
| Cinnamic Aldehyde SCHEMBL8740777 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| Benzaldehyde SCHEMBL19924275 | 0.84 | ALDH1A1 (0.47) | ALDH1A1CYP2A6KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12496370-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2025-12-16 | — | — | US | claimed |
| CN-119867364-A | Electronic atomized liquid with fruit fragrance | 思摩尔国际控股有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119614292-A | Dried apricot water-soluble essence and preparation method and application thereof | 山东将军烟草新材料科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119534683-A | Identification method of volatile biomarker of kiwi fruit soft rot and identification method of soft rot | 陕西师范大学 | 2025-02-28 | — | — | CN | claimed |
| CN-119111761-A | Guava essence and preparation method thereof | 东莞奇易香料有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-118902055-A | Apricot essence and preparation method thereof | 江西锡曼食品科技有限责任公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118452168-A | Hexagon essence and preparation method and application thereof | 上海熙美源实业有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118402594-A | Preparation method of cherry essence for carbonated beverage | 四川味欣生物科技有限公司 | 2024-07-30 | — | — | CN | claimed |
| US-11806448-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2023-11-07 | — | — | US | claimed |
| CN-112924609-B | Method for analyzing volatile aroma components contained in bead blasting filter stick | 福建中烟工业有限责任公司 | 2023-02-03 | — | — | CN | claimed |
| EP-1183053-B1 | COMPOSITION AND METHOD FOR DISINFECTING THE AIR | SCHUER JOERG-PETER PROF (DE) | 2005-04-20 | — | — | EP | claimed |
| JP-2005509662-A | — | — | 2005-04-14 | — | — | JP | claimed |
| CN-1589136-A | Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups | CUTANIX CORP (US) | 2005-03-02 | — | — | CN | claimed |
| US-20050014827-A1 | Synergistic medicament containing flavoring agents and having an antagonistic regenerative and/or protagonist decontamination effect | SCHUR JORG P (DE) | 2005-01-20 | — | — | US | claimed |
| WO-2004091307-A2 | FEED ADDITIVES AGAINST DISEASSE INFECTION IN TERRESTRIAL AND AQUATIC ANIMALS | ADVANCED BIONUTRITON CORPORATION (US) | 2004-10-28 | — | — | WO | claimed |
| EP-1443915-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | Cutanix Corporation (US) | 2004-08-11 | — | — | EP | claimed |
| US-20040076614-A1 | Symbiotic regenerative agent | SCHUR JORG P (DE) | 2004-04-22 | — | — | US | claimed |
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | CUTANIX CORPORATION | 2003-08-21 | — | — | US | claimed |
| WO-2003043621-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | CUTANIX CORPORATION (US) | 2003-05-30 | — | — | WO | claimed |
| EP-0762837-B1 | PROCESS FOR IMPROVING THE SHELF LIFE OF AND/OR STABILISING PRODUCTS WHICH CAN SPOIL UNDER THE ACTION OF MICROBES | SCHUER JOERG PETER PROF (DE) | 2002-02-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | TYR, HRH1, HRH2 | ALDH1A1 7/4885CYP2A6 353/4885KMT2A 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.