Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306650 | 0.94 | MEN1 (0.47) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL5312400 | 0.92 | MEN1 (0.48) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL5309396 | 0.86 | EGLN1 (0.43) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL5310591 | 0.84 | HIF1A (0.42) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL5308980 | 0.83 | EGLN3 (0.54) | MEN1KMT2ARXFP1EGLN1EGLN3 | |
| SCHEMBL5313516 | 0.83 | EGLN3 (0.43) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL5306234 | 0.83 | TDP1 (0.45) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL5305537 | 0.83 | TDP1 (0.45) | MEN1KMT2ARXFP1EGLN1TDP1 | |
| SCHEMBL5306838 | 0.83 | HIF1A (0.42) | MEN1KMT2ARXFP1EGLN1EGLN3 | |
| SCHEMBL5380546 | 0.82 | HIF1A (0.41) | EGLN1EGLN3TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |