Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | LAP3 | P28838 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425137 | 0.87 | PPARG (0.59) | PPARGPPARALTA4HLAP3FFAR1 | |
| SCHEMBL323396 | 0.84 | LTA4H (0.48) | LTA4HMEN1KMT2ANPC1RAB9A | |
| SCHEMBL20425275 | 0.80 | SYK (0.53) | PPARGPPARALTA4HLAP3FFAR1 | |
| SCHEMBL1552843 | 0.80 | PPARG (0.58) | PPARGPPARALTA4HLAP3FFAR1 | |
| SCHEMBL1552840 | 0.80 | PPARG (0.58) | PPARGPPARALTA4HLAP3FFAR1 | |
| SCHEMBL4230149 | 0.78 | PPARG (0.51) | PPARGPPARALTA4HFFAR1FFAR4 | |
| SCHEMBL11099777 | 0.77 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7254114 | 0.75 | PPARG (0.60) | PPARGPPARALTA4HLAP3FFAR1 | |
| SCHEMBL7254106 | 0.75 | PPARG (0.60) | PPARGPPARALTA4HLAP3FFAR1 | |
| SCHEMBL7263908 | 0.74 | PPARA (0.67) | PPARGPPARALTA4HLAP3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042878-A1 | NOVEL HETEROCYCLIC ANALOGS OF BIPHENYL ETHERS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-19 | — | — | WO | disclosed |
| WO-2006126074-A2 | HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-11-30 | — | — | WO | disclosed |