Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310112 | 0.86 | CYP1A2 (0.61) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2821289 | 0.84 | PTGDR2 (0.70) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14529178 | 0.80 | CNR1 (0.40) | PTGDR2ALDH1A1MAPT | |
| SCHEMBL2820684 | 0.79 | PTGDR2 (0.73) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL19798165 | 0.79 | PTGDR2 (0.56) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13116316 | 0.78 | PTGDR2 (0.53) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13116317 | 0.78 | PTGDR2 (0.52) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5313547 | 0.78 | KDM4E (0.55) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5312710 | 0.78 | MEN1 (0.58) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5312909 | 0.77 | KDM4E (0.54) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051133-A2 | SUBSTITUTED THIAZOLES AND THEIR USE | MUTSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-05-03 | — | — | WO | disclosed |