Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.51 |
| ▸ | LCK | P06239 | 3/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312762 | 0.93 | LCK (0.45) | KDRLCKTBK1BRAF | |
| SCHEMBL5310105 | 0.88 | KDR (0.46) | KDRLCKTBK1BRAF | |
| SCHEMBL5311465 | 0.88 | KDR (0.46) | KDRLCKTBK1 | |
| SCHEMBL5314682 | 0.86 | LCK (0.43) | KDRLCKBRAF | |
| SCHEMBL5314751 | 0.86 | LCK (0.50) | KDRLCKBRAF | |
| SCHEMBL5314806 | 0.84 | LCK (0.41) | KDRLCKBRAF | |
| SCHEMBL5310327 | 0.84 | KDR (0.53) | KDRLCKTBK1 | |
| SCHEMBL14530673 | 0.84 | KDR (0.51) | KDRLCKTBK1 | |
| SCHEMBL5316017 | 0.84 | KDR (0.51) | KDRLCKTBK1 | |
| SCHEMBL5311426 | 0.84 | KDR (0.52) | KDRLCKTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |