Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 12/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311328 | 0.93 | LCK (0.43) | KDRLCKTBK1 | |
| SCHEMBL5310105 | 0.92 | KDR (0.46) | KDRLCKTBK1 | |
| SCHEMBL5310236 | 0.91 | LCK (0.50) | KDRLCKTBK1 | |
| SCHEMBL5315162 | 0.88 | KDR (0.51) | KDRLCKTBK1 | |
| SCHEMBL5311426 | 0.87 | KDR (0.52) | KDRLCKTBK1 | |
| SCHEMBL5315703 | 0.87 | LCK (0.40) | KDRLCK | |
| SCHEMBL5312796 | 0.87 | LCK (0.40) | KDRLCK | |
| SCHEMBL5310327 | 0.85 | KDR (0.53) | KDRLCKTBK1 | |
| SCHEMBL5312989 | 0.85 | KDR (0.47) | KDRLCKTBK1 | |
| SCHEMBL5314625 | 0.84 | KDR (0.49) | KDRLCKTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |