Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.50 |
| ▸ | EGLN2 | Q96KS0 | 17/20 | 0.48 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315695 | 0.91 | EGLN1 (0.49) | EGLN1EGLN2 | |
| SCHEMBL6060364 | 0.86 | EGLN1 (0.52) | EGLN1EGLN2THRATHRB | |
| SCHEMBL3914540 | 0.85 | EGLN1 (0.70) | EGLN1EGLN2THRATHRB | |
| SCHEMBL6060946 | 0.83 | EGLN1 (0.49) | EGLN1EGLN2 | |
| SCHEMBL28911350 | 0.83 | EGLN1 (0.68) | EGLN1EGLN2 | |
| SCHEMBL6059995 | 0.81 | EGLN1 (0.56) | EGLN1EGLN2THRATHRB | |
| SCHEMBL20774561 | 0.78 | EGLN1 (0.50) | EGLN1EGLN2 | |
| SCHEMBL4111418 | 0.77 | EGLN1 (0.71) | EGLN1EGLN2THRATHRB | |
| SCHEMBL3924768 | 0.76 | EGLN2 (0.51) | EGLN1EGLN2 | |
| SCHEMBL3917940 | 0.76 | EGLN2 (0.51) | EGLN1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047194-A2 | METHODS FOR TREATING MITF-RELATED DISORDERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |