Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715118 | 0.84 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL16925204 | 0.83 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL16555998 | 0.78 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL9018854 | 0.78 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL6934720 | 0.78 | AOC3 (0.37) | CYP2C19TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL514630 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL224653 | 0.77 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL100732 | 0.77 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL30320250 | 0.77 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| Fluoride SCHEMBL28296217 | 0.76 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920135-A | Dimer impurity in ziprasidone hydrochloride raw material and preparation method thereof | 海南鑫开源医药科技有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-108003113-A | A kind of synthetic method for treating diabetes medicament | 上海工程技术大学 | 2018-05-08 | — | — | CN | claimed |
| EP-1081141-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 2005-05-04 | — | — | EP | claimed |
| EP-1081141-A1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2001-03-07 | — | — | EP | claimed |
| EP-0741129-B1 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS (JP) | 1999-06-09 | — | — | EP | claimed |
| US-5679827-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | claimed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | claimed |
| CN-108003113-B | Synthetic method of medicine for treating diabetes | 上海工程技术大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-108003113-B | Synthetic method of medicine for treating diabetes | 上海工程技术大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-112920135-A | Dimer impurity in ziprasidone hydrochloride raw material and preparation method thereof | 海南鑫开源医药科技有限公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-108003113-A | A kind of synthetic method for treating diabetes medicament | 上海工程技术大学 | 2018-05-08 | — | — | CN | disclosed |
| CN-108003113-A | A kind of synthetic method for treating diabetes medicament | 上海工程技术大学 | 2018-05-08 | — | — | CN | disclosed |
| US-9346795-B2 | Substituted sulfonamides useful as antiapoptotic Bcl inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-5773626-A | HALOGENATION OF A 2-(ALKYLTHIO)BENZALDEHYDE OXIME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| US-5756806-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5679827-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| US-5633384-A | FROM O-ALKYLTHIOBENZONITRILES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |