Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427756 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL72183 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL944584 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL28228479 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28874104 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27584626 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL6759280 | 0.78 | MAPK1 (0.33) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL27306666 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL27305380 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL7937247 | 0.72 | KCNN4 (0.39) | ALDH1A1POLBTDP1L3MBTL1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720590-A | [2,2,2-trihalo-1-(trihalomethyl)]ethylidene-bisbenzenethiols | HUGHES AIRCRAFT COMPANY (US) | 1988-01-19 | — | — | US | claimed |
| EP-0129561-B1 | 2,2,2-TRIHALO-1-(TRIHALOMETHYL)ETHYLIDENE-BISBENZENETHIOLS | Hughes Aircraft Company (US) | 1986-02-12 | — | — | EP | claimed |
| EP-0129561-A1 | 2,2,2-TRIHALO-1-(TRIHALOMETHYL)ETHYLIDENE-BISBENZENETHIOLS. | HUGHES AIRCRAFT CO (US) | 1985-01-02 | — | — | EP | claimed |
| WO-1984002524-A1 | 2,2,2-TRIHALO-1-(TRIHALOMETHYL)ETHYLIDENE-BISBENZENETHIOLS | HUGHES AIRCRAFT CO (US) | 1984-07-05 | — | — | WO | claimed |
| WO-2007079004-A2 | FLUORINATED POLYARYLENETHIOETHERSULFONE POLYMERS HAVING SULFONATE PENDANTS AND PHENYL-ENDCAPPING GROUPS FOR USE AS PROTON EXCHANGE MEMBRANES | UNIVERSITY OF DAYTON (US) | 2007-07-12 | — | — | WO | disclosed |
| JP-2006009026-A | FLUORINE-CONTAINING ELASTOMER COMPOSITION | YUNIMATEKKU KK | 2006-01-12 | — | — | JP | disclosed |
| US-5998564-A | CURING AGENT FOR FLUOROPOLYMERS | NIPPON MEKTRON, LIMITED (JP) | 1999-12-07 | — | — | US | disclosed |
| US-4720590-A | [2,2,2-trihalo-1-(trihalomethyl)]ethylidene-bisbenzenethiols | HUGHES AIRCRAFT COMPANY (US) | 1988-01-19 | — | — | US | disclosed |