Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ITK | Q08881 | 17/20 | 0.47 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315661 | 0.89 | CNR2 (0.49) | CNR2ITK | |
| SCHEMBL5317405 | 0.83 | PTGER4 (0.52) | CNR2ITK | |
| SCHEMBL5317411 | 0.83 | PTGER4 (0.53) | CNR2 | |
| SCHEMBL5317545 | 0.83 | ITK (0.44) | CNR2ITK | |
| SCHEMBL5315622 | 0.77 | TLR9 (0.46) | ITKMRGPRX2 | |
| SCHEMBL5316334 | 0.75 | CNR2 (0.52) | CNR2ITK | |
| SCHEMBL5315402 | 0.73 | CNR2 (0.48) | CNR2ITKMRGPRX2 | |
| SCHEMBL5315400 | 0.72 | FLT3 (0.48) | ITK | |
| SCHEMBL5320783 | 0.72 | ITK (0.47) | ITKMRGPRX2 | |
| SCHEMBL5318212 | 0.72 | JAK2 (0.49) | CNR2ITKMRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |