Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | ITK | Q08881 | 18/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318297 | 0.90 | CNR2 (0.51) | CNR2ITKPTGER4 | |
| SCHEMBL5316800 | 0.83 | PTGER4 (0.49) | CNR2PTGER4 | |
| SCHEMBL5315360 | 0.82 | ITK (0.43) | CNR2ITKPTGER4 | |
| SCHEMBL5315618 | 0.81 | PTGER4 (0.51) | CNR2PTGER4 | |
| SCHEMBL5320779 | 0.80 | HRH3 (0.47) | CNR2PTGER4 | |
| SCHEMBL5320022 | 0.78 | ADORA2A (0.49) | CNR2ITK | |
| SCHEMBL5315599 | 0.75 | CNR2 (0.49) | CNR2ITK | |
| SCHEMBL5318212 | 0.73 | JAK2 (0.49) | CNR2ITK | |
| SCHEMBL5317398 | 0.73 | ITK (0.49) | CNR2ITK | |
| SCHEMBL5318430 | 0.72 | ITK (0.49) | CNR2ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |