Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 11/20 | 0.45 |
| ▸ | MAOA | P21397 | 9/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28350007 | 0.73 | KCNA3 (0.54) | MRGPRX4MAOBMAOAADRB2ADRB1 | |
| SCHEMBL11806193 | 0.73 | MRGPRX4 (0.53) | MRGPRX4MAOBMAOAADRB2ADRB1 | |
| SCHEMBL11127019 | 0.72 | ABCB1 (0.53) | MRGPRX4ADRB2ADRB1HTR1AADRB3 | |
| SCHEMBL28986027 | 0.72 | MRGPRX4 (0.54) | MRGPRX4MAOBMAOAADRB2ADRB1 | |
| SCHEMBL13481244 | 0.72 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1HTR1AADRB3 | |
| SCHEMBL30317439 | 0.72 | MRGPRX4 (0.54) | MRGPRX4MAOBMAOAADRB2ADRB1 | |
| SCHEMBL28346669 | 0.72 | MAOB (0.50) | MRGPRX4MAOBMAOAADRB2ADRB1 | |
| SCHEMBL5149581 | 0.72 | MRGPRX4 (0.46) | MRGPRX4MAOBMAOAADRB2ADRB1 | |
| SCHEMBL5316394 | 0.71 | HCAR2 (0.40) | MAOB | |
| SCHEMBL1400472 | 0.71 | PPARD (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071456-A1 | FLUORENES AND CARBAZOLES AS LIGANDS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | WO | disclosed |