SCHEMBL5315671

SCHEMBL5315671

Nc1ccc(C=CC(=O)Nc2ccc(N)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 10/20 0.71
MMP2 P08253 10/20 0.71
MMP9 P14780 10/20 0.71
KDM1A O60341 1/20 0.65
EGFR P00533 5/20 0.62
MAOB P27338 2/20 0.62
MAOA P21397 1/20 0.62
DEGS1 O15121 1/20 0.60
LMNA P02545 1/20 0.58
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA9 Q16790 2/20 0.57
TOP2A P11388 1/20 0.56
TP53 P04637 1/20 0.56
MAPT P10636 1/20 0.56
THRB P10828 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20251150 1.00 MMP1 (0.71) MMP1MMP2MMP9KDM1AEGFR
SCHEMBL28278711 0.93 MMP1 (0.84) MMP1MMP2MMP9KDM1AMAOB
SCHEMBL31501465 0.91 EGFR (0.77) MMP1MMP2MMP9EGFRMAOB
SCHEMBL28937301 0.86 MMP1 (0.78) MMP1MMP2MMP9KDM1A
SCHEMBL11704923 0.83 MMP1 (1.00) MMP1MMP2MMP9KDM1AEGFR
SCHEMBL12425705 0.82 HDAC2 (0.64)
SCHEMBL2635122 0.82 HDAC2 (0.64)
SCHEMBL13425358 0.81 MMP1 (0.87) MMP1MMP2MMP9EGFRMAOB
SCHEMBL20537700 0.81 KDM1A (0.74) KDM1ALMNACA12CA1CA2
SCHEMBL20537704 0.81 KDM1A (0.74) KDM1ALMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070161775-A1 Novel polyimide and method for preparing the same LG CHEM, LTD. (KR) 2007-07-12 US claimed
WO-2007064156-A1 NOVEL POLYIMIDE AND METHOD FOR PREPARING THE SAME LG CHEM. LTD. (KR) 2007-06-07 WO claimed
JP-59145216-A None JP disclosed
US-20070161775-A1 Novel polyimide and method for preparing the same LG CHEM, LTD. (KR) 2007-07-12 US disclosed
WO-2007064160-A1 METHOD OF PRODUCING LIQUID CRYSTAL ALIGNING LAYER, LIQUID CRYSTAL ALIGNING LAYER PRODUCED USING THE SAME, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEM. LTD. (KR) 2007-06-07 WO disclosed
US-20070128378-A1 Method of producing liquid crystal aligning layer, liquid crystal aligning layer produced using the same, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2007-06-07 US disclosed
WO-2007064156-A1 NOVEL POLYIMIDE AND METHOD FOR PREPARING THE SAME LG CHEM. LTD. (KR) 2007-06-07 WO disclosed
JP-S59145216-A ORGANIC SOLVENT-SOLUBLE PHOTOSENSITIVE POLYAMIDE-IMIDE UBE IND LTD 1984-08-20 JP disclosed