Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315686 | 0.95 | PRKCA (0.42) | PRKCAMMP12NR1I2SCN9AOXTR | |
| SCHEMBL5198409 | 0.89 | GRIN2B (0.43) | PRKCAMMP12NR1I2SCN9AGRIN2B | |
| SCHEMBL5439046 | 0.89 | PRKCA (0.44) | PRKCAMMP12NR1I2SCN9AGRIN2B | |
| SCHEMBL5196260 | 0.87 | GRIN2B (0.40) | PRKCAMMP12NR1I2SCN9AGRIN2B | |
| SCHEMBL5198064 | 0.87 | SCN7A (0.43) | PRKCAMMP12NR1I2SCN9AGRIN2B | |
| SCHEMBL5934915 | 0.86 | SCN7A (0.38) | PRKCAMMP12NR1I2SCN9AGRIN2B | |
| SCHEMBL5197980 | 0.85 | GRIN2B (0.43) | PRKCAMMP12NR1I2SCN9AGRIN2B | |
| SCHEMBL5198351 | 0.85 | PRKCA (0.44) | PRKCAMMP12NR1I2SCN9AGRIN2B | |
| SCHEMBL5223713 | 0.84 | PRKCA (0.43) | PRKCAMMP12NR1I2SCN9AOXTR | |
| SCHEMBL5217612 | 0.83 | SCN9A (0.41) | PRKCAMMP12NR1I2SCN9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844042-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006076529-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2006-07-20 | — | — | WO | disclosed |