Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 3/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495087 | 0.92 | CHRNA7 (0.51) | CHRNA7WDR5SCN2ASCN10AHDAC1 | |
| SCHEMBL5314889 | 0.91 | CHRNA7 (0.57) | CHRNA7PDGFRAKDRSCN2ASCN10A | |
| SCHEMBL14494779 | 0.88 | CHRNA7 (0.53) | CHRNA7WDR5SCN2ASCN10AHDAC1 | |
| SCHEMBL5313234 | 0.84 | CHRNA7 (0.49) | CHRNA7PDGFRAKDRWDR5BTK | |
| SCHEMBL5317038 | 0.83 | BTK (0.57) | CHRNA7PDGFRAKDRBTKITK | |
| SCHEMBL5315413 | 0.82 | CHRNA7 (0.57) | CHRNA7SCN2ASCN10AHDAC1S1PR4 | |
| SCHEMBL5312257 | 0.80 | CHRNA7 (0.61) | CHRNA7PDGFRAKDRBTKSCN2A | |
| SCHEMBL14494780 | 0.78 | CHRNA7 (0.59) | CHRNA7SCN2ASCN10AHDAC1S1PR4 | |
| SCHEMBL5312509 | 0.78 | CHRNA7 (0.53) | CHRNA7SCN2ASCN10AS1PR4CTSA | |
| SCHEMBL14494777 | 0.78 | CHRNA7 (0.55) | CHRNA7BTKSCN2ASCN10AS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062459-A1 | SELECTIVE KINASE INHIBITORS BASED ON PYRIDINE SCAFFOLD | CYTOPIA RESEARCH PTY LTD (AU) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007062459-A1 | SELECTIVE KINASE INHIBITORS BASED ON PYRIDINE SCAFFOLD | CYTOPIA RESEARCH PTY LTD (AU) | 2007-06-07 | — | — | WO | disclosed |