Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 11/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315807 | 0.92 | PSEN1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5155933 | 0.85 | FABP4 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5151258 | 0.84 | FABP4 (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5156668 | 0.79 | KDM4E (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5155238 | 0.78 | PSEN1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5154718 | 0.78 | KDM4E (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5156083 | 0.77 | KDM4E (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5151860 | 0.76 | KDM4E (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5149567 | 0.76 | FABP4 (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5151535 | 0.75 | FABP4 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071456-A1 | FLUORENES AND CARBAZOLES AS LIGANDS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | WO | claimed |