Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | PGR | P06401 | 1/20 | 0.72 |
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | DRD1 | P21728 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.72 |
| ▸ | DRD3 | P35462 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.51 |
| ▸ | PRKCG | P05129 | 2/20 | 0.51 |
| ▸ | PRKCB | P05771 | 2/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.51 |
| ▸ | PRKCH | P24723 | 2/20 | 0.51 |
| ▸ | PRKCI | P41743 | 2/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656637 | 0.92 | ESR1 (0.61) | ESR1PGRHTR1ADRD1PTGS1 | |
| SCHEMBL6156991 | 0.88 | ESR1 (0.65) | ESR1PGRHTR1ADRD1PTGS1 | |
| SCHEMBL11072984 | 0.88 | GSK3B (0.81) | ESR1PGRHTR1ADRD1PTGS1 | |
| SCHEMBL6157510 | 0.86 | ESR1 (0.63) | ESR1PGRHTR1ADRD1PTGS1 | |
| SCHEMBL14424698 | 0.86 | ESR1 (0.83) | ESR1PGRHTR1ADRD1PTGS1 | |
| SCHEMBL11072864 | 0.85 | GSK3B (0.80) | ESR1PGRHTR1ADRD1PTGS1 | |
| SCHEMBL30352837 | 0.85 | ESR1 (0.64) | ESR1PGRHTR1ADRD1PTGS1 | |
| SCHEMBL19715447 | 0.85 | ESR1 (0.64) | ESR1PGRHTR1ADRD1PTGS1 | |
| Tafenoquine SCHEMBL31160547 | 0.84 | ESR1 (1.00) | ESR1PGRHTR1ADRD1PTGS1 | |
| Tafenoquine SCHEMBL29450724 | 0.84 | ESR1 (1.00) | ESR1PGRHTR1ADRD1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056580-A2 | METHODS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH PATHOGENIC PROTEINS | PHARMADYN, INC. (US) | 2007-05-18 | — | — | WO | disclosed |