SCHEMBL5315930

SCHEMBL5315930

CNc1ccccc1CCCO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.40
KDM4E B2RXH2 4/20 0.38
POLB P06746 4/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TMEM97 Q5BJF2 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
USP2 O75604 1/20 0.38
RECQL P46063 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
AR P10275 1/20 0.37
SLC16A3 O15427 2/20 0.37
ATM Q13315 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
LIPG Q9Y5X9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27603742 0.94 SLC16A3 (0.39) TRPV1KDM4EPOLBALDH1A1MAPT
Carbamic Acid SCHEMBL28108904 0.90 SLC16A3 (0.41) TRPV1KDM4EPOLBALDH1A1HPGD
SCHEMBL932125 0.88 TDP1 (0.40) TRPV1KDM4EPOLBALDH1A1MAPT
SCHEMBL22535153 0.87 L3MBTL1 (0.43) KDM4EPOLBALDH1A1MAPTHPGD
SCHEMBL2640713 0.84 SLC16A3 (0.39) KDM4ETMEM97SLC16A3GAATSHR
SCHEMBL27477308 0.83 TSHR (0.37) KDM4EPOLBALDH1A1MAPTTMEM97
SCHEMBL4093561 0.82 CYP3A4 (0.45) KDM4EPOLBALDH1A1MAPTHPGD
SCHEMBL8283669 0.81 POLB (0.41) TRPV1KDM4EPOLBALDH1A1MAPT
SCHEMBL17750801 0.80 TAAR1 (0.41) KDM4EPOLBALDH1A1MAPTHPGD
SCHEMBL17750799 0.80 KDM4E (0.38) KDM4EPOLBALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111803474-A Application of ephedrine in treating Parkinson's disease 云南帕精生物科技有限公司 2020-10-23 CN claimed
CN-107630049-A The biological preparation method of ephedrine 武汉茵茂特生物技术有限公司 2018-01-26 CN claimed
CN-106458866-A Aminocarbonyl carbamate compound 爱思开生物制药株式会社 2017-02-22 CN claimed
EP-1527034-A1 A PROCESS FOR THE OPTICAL RESOLUTION OF A PRECURSOR OF SCLAREOLIDE FIRMENICH SA (CH) 2005-05-04 EP claimed
WO-2004013069-A1 A PROCESS FOR THE OPTICAL RESOLUTION OF A PRECURSOR OF SCLAREOLIDE FIRMENICH SA (CH) 2004-02-12 WO claimed
EP-1299342-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2003-04-09 EP claimed
WO-2002004399-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2002-01-17 WO claimed
CN-111803474-A Application of ephedrine in treating Parkinson's disease 云南帕精生物科技有限公司 2020-10-23 CN disclosed
WO-2018000098-A1 TREATMENT OF INFLAMMATORY MYOPATHIES CIPHER PHARMACEUTICALS INC. (CA) 2018-01-04 WO disclosed
CN-106841405-A A kind of relevant substance detecting method of ephedrine hydrochloride piece 康普药业股份有限公司 2017-06-13 CN disclosed
CN-106458866-A Aminocarbonyl carbamate compound 爱思开生物制药株式会社 2017-02-22 CN disclosed
EP-2116544-B1 Spirocyclic cyclohexane derivatives GRUENENTHAL GMBH (DE) 2016-05-18 EP disclosed
EP-2233487-B1 Spirocyclic cyclohexane derivatives GRUENENTHAL GMBH (DE) 2016-05-18 EP disclosed
EP-1299342-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2003-04-09 EP disclosed
WO-2002004399-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2002-01-17 WO disclosed
EP-1165570-A2 NOVEL PHOSPHORUS-CONTAINING PRODRUGS Metabasis Therapeutics, Inc. (US) 2002-01-02 EP disclosed
WO-2000052015-A2 NOVEL PHOSPHORUS-CONTAINING PRODRUGS METABASIS THERAPEUTICS, INC. (US) 2000-09-08 WO disclosed
WO-2000023046-A1 CHEWABLE OR DISSOLVABLE PHARMACEUTICAL COMPOSITIONS SUITABLE FOR ORAL ADMINISTRATION BUSH BOAKE ALLEN INC. (US) 2000-04-27 WO disclosed
WO-1999067196-A1 FLUOXETINE PROCESS FROM BENZOYLPROPIONIC ACID SEPRACOR INC. (US) 1999-12-29 WO disclosed
US-4277420-A Ephedrine and pseudoephedrine precursors MONSANTO COMPANY (US) 1981-07-07 US disclosed