Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448539 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL7448533 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL7142898 | 0.77 | SMPD2 (0.43) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL7448373 | 0.77 | SMPD2 (0.43) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL5229233 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL10515353 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL1812242 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL10414190 | 0.75 | ALDH1A1 (0.44) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL10414188 | 0.75 | ALDH1A1 (0.44) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL7424413 | 0.75 | ALDH1A1 (0.44) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007048557-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-05-03 | — | — | WO | disclosed |